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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CUL5
All Species:
27.27
Human Site:
S220
Identified Species:
42.86
UniProt:
Q93034
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q93034
NP_003469.2
780
90955
S220
F
Y
R
T
Q
A
P
S
Y
L
Q
Q
N
G
V
Chimpanzee
Pan troglodytes
XP_001137909
721
84087
M203
C
N
S
V
E
A
L
M
E
C
C
V
N
A
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_546540
811
94684
S251
F
Y
R
T
Q
A
P
S
Y
L
Q
Q
N
G
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9D5V5
780
90956
S220
F
Y
R
T
Q
A
P
S
Y
L
Q
Q
N
G
V
Rat
Rattus norvegicus
Q9JJ31
780
90872
S220
F
Y
R
T
Q
A
P
S
Y
L
Q
Q
N
G
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508663
779
91022
S219
F
Y
R
T
Q
A
P
S
Y
L
Q
Q
N
G
V
Chicken
Gallus gallus
XP_417163
809
94020
S249
F
Y
R
T
Q
A
P
S
Y
L
Q
Q
N
G
V
Frog
Xenopus laevis
Q6GPF3
768
88937
K223
F
F
Q
M
E
S
Q
K
F
L
A
E
N
S
A
Zebra Danio
Brachydanio rerio
XP_001922879
780
90814
S220
F
Y
K
T
Q
A
P
S
Y
L
Q
Q
N
G
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24311
774
89493
V218
A
E
Q
Q
K
L
S
V
Y
K
Q
N
F
E
N
Honey Bee
Apis mellifera
XP_623958
789
91733
E223
F
Y
W
V
K
A
P
E
Q
L
S
L
H
G
V
Nematode Worm
Caenorhab. elegans
Q23639
765
88890
N205
Y
Y
K
K
I
C
G
N
L
L
N
E
L
G
V
Sea Urchin
Strong. purpuratus
XP_787630
787
91852
N235
F
Y
K
A
Q
A
P
N
Y
L
A
E
N
G
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94AH6
738
86284
R206
D
T
S
S
Y
Y
S
R
K
A
S
S
W
I
Q
Baker's Yeast
Sacchar. cerevisiae
Q12018
815
93926
Q238
K
T
Q
E
Y
Y
T
Q
Y
T
N
D
Y
L
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.4
N.A.
95.8
N.A.
98.4
98.7
N.A.
98.8
95.6
27.3
95.1
N.A.
29.7
72.3
51.4
72.9
Protein Similarity:
100
92.4
N.A.
96
N.A.
99.6
99.6
N.A.
99.2
96.1
50.2
98.3
N.A.
51.2
83.4
69.3
84.5
P-Site Identity:
100
13.3
N.A.
100
N.A.
100
100
N.A.
100
100
20
93.3
N.A.
13.3
46.6
26.6
66.6
P-Site Similarity:
100
26.6
N.A.
100
N.A.
100
100
N.A.
100
100
60
100
N.A.
26.6
60
53.3
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.2
23.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
48.2
44.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
7
0
67
0
0
0
7
14
0
0
7
7
% A
% Cys:
7
0
0
0
0
7
0
0
0
7
7
0
0
0
0
% C
% Asp:
7
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% D
% Glu:
0
7
0
7
14
0
0
7
7
0
0
20
0
7
7
% E
% Phe:
67
7
0
0
0
0
0
0
7
0
0
0
7
0
0
% F
% Gly:
0
0
0
0
0
0
7
0
0
0
0
0
0
67
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% H
% Ile:
0
0
0
0
7
0
0
0
0
0
0
0
0
7
0
% I
% Lys:
7
0
20
7
14
0
0
7
7
7
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
7
7
0
7
74
0
7
7
7
7
% L
% Met:
0
0
0
7
0
0
0
7
0
0
0
0
0
0
0
% M
% Asn:
0
7
0
0
0
0
0
14
0
0
14
7
67
0
7
% N
% Pro:
0
0
0
0
0
0
60
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
20
7
54
0
7
7
7
0
54
47
0
0
7
% Q
% Arg:
0
0
40
0
0
0
0
7
0
0
0
0
0
0
0
% R
% Ser:
0
0
14
7
0
7
14
47
0
0
14
7
0
7
0
% S
% Thr:
0
14
0
47
0
0
7
0
0
7
0
0
0
0
0
% T
% Val:
0
0
0
14
0
0
0
7
0
0
0
7
0
0
67
% V
% Trp:
0
0
7
0
0
0
0
0
0
0
0
0
7
0
0
% W
% Tyr:
7
67
0
0
14
14
0
0
67
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _